She was the daughter of Hendrik van der Merwe and Johanna Catharina Lubbe
Sources
[1] Her baptism record on 21 April 1782 in Cape Town gives name and relationship to parents.
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DNA Connections
It may be possible to confirm family relationships with Anna Sophia by comparing test results with other carriers of her ancestors' mitochondrial DNA.
However, there are no known mtDNA test-takers in her direct maternal line.
It is likely that these autosomal DNA test-takers will share some percentage of DNA with Anna Sophia: